CD55 antibody (PE)

Catalog No. ABIN951352

This Mouse Monoclonal antibody specifically detects CD55 in FACS. It exhibits reactivity toward Human and Primate.

Quick Overview for CD55 antibody (PE) (ABIN951352)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD55 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: MEM-118

Product Details anti-CD55 Antibody (PE)

Specificity: This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.

Cross-Reactivity (Details): Species reactivity (tested):Human, Non-Human Primates

Isotype: IgM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55 / DAF

Background: CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.Synonyms: Complement decay-accelerating factor

Gene ID: 1604

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity